A look at what’s happening in European football on Tuesday:

England

Arsenal returns to Southampton on Tuesday fresh from being knocked out of the FA Cup there on Saturday. Manager Mikel Arteta made 7 changes for the game but is expected to restore Bukayo Saka, Thomas Partey, Kieran Tierney and Emile Smith Rowe into the Arsenal lineup. A win might move Arsenal within four points of the leading 4, having been languishing just above the relegation zone last month. West Ham might burglarize the top four with a success at Crystal Palace. Newcastle hosts Leeds without a win in 10 games in all competitors and having gathered only two points from its last eight Premier League matches. Steve Bruce’s side has just one goal in its last eight matches. Leeds are bidding to avoid a fourth straight defeat after two league losses sandwiched a humbling FA Cup exit versus lowly Crawley.

Spain

The round of 16 of the Copa del Rey starts with a set of matches between first-division clubs. Valladolid hosts Levante to start the day, then Real Sociedad visits Real Betis. Valladolid and Levante remain in the bottom half of the Spanish league, while Sociedad and Betis are closer to the top. Villarreal sees second-division club Girona in the only other Copa match. The round of 16 is still played in one-game matchups.

Italy

Inter Milan and city rival AC Milan are contending for the Serie A title but fulfill on Tuesday with a place in the Italian Cup semifinals at stake. The winner will next play Juventus or Spal, who fulfill on Wednesday. Milan required charges to beat Torino to reach the quarterfinals while Romelu Lukaku scored at the end of extra time to secure Inter a 2-1 win over Fiorentina and its place in the last eight. Both Milan teams had frustrating outcomes in the league last weekend but the Rossoneri stayed top, 2 points above second-placed Inter. Inter has won the Italian Cup seven times, but not considering that 2011. Milan won the last of its five Italian Cup prizes in 2003.

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